Stat-Ease Blog

Design of experiments (DOE), being such an effective combination of multifactor testing with statistical tools, hits the spot for engineers and scientists doing industrial R&D. However, as documented in my white paper on Achieving Breakthroughs in Non-Manufacturing Processes via Design of Experiments (DOE), this statistical methodology works equally well for business processes. Yet, non-manufacturing experimenters rarely make it beyond simple one-factor-at-a-time (OFAT) comparisons known as A/B splits—most recently embraced, to my great disappointment, by Harvard Business Review*. But to give HBR some credit, this 2017 feature on experimentation at least mentions “multivariate” (I prefer “multifactor”) testing as a better alternative.

To see an illuminating example of multifactor testing applied to marketing, see my April 21 StatsMadeEasy blog: Business community discovers that “Experimentation Works”.

Another great case for applying multifactor DOE came from Kontsevaia and Berger in a study published by the International Journal of Business, Economics and Managemental**. To maximize impressions per social-media posts, they applied a fractional two-level design on 6 factors in 16 runs varying:

A. Type of Day/Day of the week: Weekend (Sat, Sun) vs Workday (Thu, Fri)

B. Social Media Channel: LinkedIn vs Twitter

C. Image present: No vs Yes

D. Time of Day: Afternoon (3-6pm) vs Morning (7-10am)

E. Length of Message: Long (at least 70 characters) vs Short (under 70 characters)

F. Hashtag present: No vs Yes

The multifactor marketing test revealed the choice of channel for maximum impressions to be highly dependent on posts going out on weekends versus workdays. This valuable insight on a two-factor interaction (AB) would never have been revealed by a simple OFAT split.

Design-Expert® software makes multifactor business experiments like this very easy for non-statisticians to design, analyze and optimize for greatly increased returns. Aided by Stat-Ease you can put DOE to work for your enterprise and make a big hit career-wise.

*“Building a Culture of Experimentation”, Stefan Thomke, March-April, 2020.

**“Analyzing Factors Affecting the Success of Social Media Posts for B2B Networks: A Fractional-Factorial Design Approach”, August, 2020.

If you haven't discovered Mark Anderson's Stats Made Easy blog yet, check it out!  Mark offers a wry look at all things statistical and/or scientific from an engineering perspective. You will find posts on topics as varied as nature, science, sports, politics, and DOE.  His latest post, Magic of multifactor testing, involves a fun DOE with bouncy balls. 

The first article follows the setup of Mark's DOE. At the bottom of Part 1, click on the Related Links tab to find Part 2 (Results) and Part 3 (Data and Details)

The 2020 Online DOE Summit was a remarkable success! If you missed any of it, read on!

We just wrapped up our 2020 Online DOE Summit. What a successful summit. A group of influential speakers kicked off the discussion of design of experiments (DOE). Hundreds of attendees logged in to each talk and soaked up that knowledge. Thank you to everyone who participated.

We created the summit because of the COVID-19 pandemic. Originally scheduled for the middle of June, our 8th European DOE Meeting was canceled in January. So, after thinking about it for a bit, we decided to move the meeting online. This would be the only way to have a meeting for a while. Plus, the cost to the audience would be zero.

All the speakers who agreed to speak at the European meeting agreed to make the move to a virtual event. A schedule was set-up. We gave it a new name. We sent emails to everyone with dates. The 2020 Online DOE Summit was born.

Our first group of presentations consisted of a kickoff talk, three keynotes, and a tutorial. Many of these talks revolved around current directions in DOE. Even though DOE has been around for decades, it is an evolving practice with new techniques and advice coming up all the time. Each speaker discussed broad concepts in design of experiments.

[Click on the title of the talk for a video recording of the presentation.]

Kickoff: Know the SCOR for Multifactor Strategy of Experimentation
Mark Anderson: Principal of Stat-Ease, Inc.
Talk Topic: Laying out a strategy for multifactor design of experiments

Keynote: My Lifelong Journey with DOE
Pat Whitcomb: Founding Principal of Stat-Ease, Inc.
Talk topic: Pat explores his lifetime of design of experiments with a view to the future

Keynote: Some Experiences in Modern Experimental Design
Marcus Perry: Editor in Chief, Quality Engineering; Professor of Statistics, The University of Alabama
Talk topic: Handling non-standard situations in today’s DOE environment

Keynote: Innovative Mixture-Process Models
Geoff Vining: Professor of Statistics, Virginia Tech
Talk Topic: An overview of KCV designs that limit runs in experiments involving both mixture components and process variables

Tutorial: Strategies for Sequential Experimentation
Martin Bezener: Director of Research & Development, Stat-Ease, Inc.
Talk Topic: This presentation explores how it may be more efficient to divide an experiment into smaller pieces. Learn how to use resources in a smarter, more adaptive manner.

In the second week of the summit, we had a separate set of talks. Each one detailed real-world experiments. Presenters discussed the actual experiments they had worked on, and how they used DOE in each case.

Simultaneous and Quick Determination of Two Ingredients Concentrations in a Solution Using a UV-Vis Spectroscopy Chemometric Model
Samd Guizani: Process Scientist, Ferring International Center

Use of DOE for 3D Printer Ink Formulation Development
Uri Zadok: Senior Research Chemist, Stratasys

Using Experimental Design to Optimize the Surfactant Package Properties of a Metalworking Cleaner
Mathijs Uljé: Development Chemist, Quaker Houghton

Optimizing Multi-Step Processes with DoE – A Cryopreservation Protocol for Plant Cells as a Case
Johannes Buyel: Head of Department of Bioprocess Engineering, Aachen University

In all, this was a great summit. The presenters were spot on with the current state of DOE, whether in modern concepts or real-life experiments. The audience took away many useful ideas and practices. It was a classic case of making lemonade from lemons.

Thanks all!

Keep your experiment planned, but random

When I wrote my introduction to factorial design (Greg’s DOE Adventure - Factorial Design, Part 1), there were a couple of points that I left out. I’ll amend that post here to talk about making sure your experiment is planned out yet random.

Wait. What?

You’ll see. Let me explain.

Getting organized

During the initial phase of an experiment, you should make sure that it is well planned out. First, think about the factors that affect the outcome of your experiment. You want to create a list that’s as all-encompassing as possible. Anything that may change the outcome, put on your list. Then pare it down into the ones that you know are going to be the biggest contributors.

Once you have done that, you can set the levels at which to run each factor. You want the low and high levels to be as far apart as possible. Not too low that you won’t see an effect (if your experiment is cooking something, don’t set the temperature so low that nothing happens). Not too high that it’s dangerous (as in cooking, you don’t want to burn your product).

Finally, you want to make sure your experiment is balanced when it comes to the factors in your experiment. Taking the cooking example above a little further, suppose you have three factors you are testing: time, temperature, and ingredient quality. Let’s also say that you are testing at two different levels: low and high (symbolized by minus and plus signs, respectively). We can write this out in a table:

This table contains all the possible combinations of the three factors. It’s called an ‘orthogonal array’ because it’s balanced. Each column has the same number of pluses and minuses (4 in this case). This balance in the array allows all factors to be uncorrelated and independent from each other.

With these steps, you have ensured that your experiment is well planned out and balanced when looking at your factors.

Always randomize

At the start of this post, I said that an experiment should be planned out, yet random. Well we have the planned-out part, now let’s get into the random part.

In any experimentation, influence from external sources (variables you are not studying) should be kept to a minimum. One way to do this is randomizing your runs.

As an example, let’s look at the table above with the cooking example. Let’s say that it represents the order of how the experiment was run. So, all the low temperature runs were made together and then all the high ones together. This makes sense, right? Perform all the runs at one temperature before adjusting up to the next setting.

The problem is, what if there is an issue with your oven that causes the temperature to fluctuate more, early in the experiment and less later. This time-related issue introduces variation (bias) into your results that you didn’t know about.

To reduce the influence of this variable, randomize your run order. It may take more time adjusting your oven for every run, but it will remove that unwanted variation.

Temperature is a popular example to illustrate randomization. But this can be said of any factor that may have time-related problems. It could be warm-up time on a machine or the physical tiring of an operator. Randomization is used to guard against bias as much as you can when running an experiment.

Conclusions

Hopefully, you see now why I said to keep your experiments planned but random. It sounds like an oxymoron, but it’s not. Not in the way I’m talking about it here!

Stat-Ease is here for you during these trying times. We can help you with your design and analysis of experiments, whether at home or in the lab. Please reach out if you have a question, sales@statease.com

A summary of information that may be important to you

Access to Design-Expert® software while working at home:

1. Download a free trial at www.statease.com/trial/. (Used your DX12 trial already? Ask us!)
2. Network users - temporarily bring a license home by checking out a roaming license from your server. Go to www.statease.com/docs/v12/network-installation/#roaming-licenses for more information.
3. Need Technical Assistance? Email support@statease.com

Access to FREE educational materials:

1. Elearning - learn DOE on demand at the Stat-Ease Academy. Go to www.statease.com/training/academy/ to sign up.
2. Hear from our DOE experts: visit our Webinars page at www.statease.com/webinars/ and our YouTube channel, www.youtube.com/channel/UCzf_5--odkQ4w25m5r09bWA
3. Dive into Design-Expert software: Tutorials (www.statease.com/docs/v12/tutorials/)

2020 European Conference: Our conference (www.statease.com/events/doe-user-meetings/8th-european-doe-meeting/) is being re-imagined into an online opportunity that will be accessible to our global audience!

To receive information by email, go to www.statease.com/publications/signup/ and signup for our email list.

If you have other needs while transitioning to a new work setup, or an Academic online learning environment, please contact sales@statease.com